{"id":155559,"date":"2023-04-15T01:26:22","date_gmt":"2023-04-15T01:26:22","guid":{"rendered":"https:\/\/culture.org\/?p=155559"},"modified":"2023-04-15T01:26:22","modified_gmt":"2023-04-15T01:26:22","slug":"new-findings-on-brain-activity-in-eating-disorders","status":"publish","type":"post","link":"https:\/\/culture.org\/special-interest\/new-findings-on-brain-activity-in-eating-disorders\/","title":{"rendered":"New Findings on Brain Activity in Eating Disorders"},"content":{"rendered":"           <!--  <script type=\"text\/javascript\">\r\n                jQuery(document).ready(function() {\r\n                    jQuery(\".key-accordion-item .key-menu\").on(\"click\", function() {\r\n                        if (jQuery(this).parent().hasClass(\"active\")) {\r\n                            jQuery(this).next().slideUp();\r\n                            jQuery(this).parent().removeClass(\"active\");\r\n                        } else {\r\n                            jQuery(\".key-content\").slideUp();\r\n                            jQuery(\".key-accordion-item\").removeClass(\"active\");\r\n                            jQuery(this).parent().addClass(\"active\");\r\n                            jQuery(this).next().slideDown();\r\n                        }\r\n                    });\r\n                })\r\n            <\/script> -->\r\n\r\n\r\n            <!-- start html -->\r\n\r\n            <div class=\"news-key-takeaway-wapper\">\r\n                                <span style=\"background-color:#39b54a;\">Key Takeaways<\/span>\r\n                <ul class=\"news-key-nbox\" style=\"border-color:#39b54a;background-color:rgba(57, 181, 74, 0.1);\">\r\n                                                        <li>Brain scans of individuals with binge-eating disorder or bulimia reveal altered activity in areas linked to habit formation, suggesting the potential for new treatments for these conditions.<\/li>\r\n                                                                    <li>The sensorimotor putamen and the associative caudate are two brain structures involved in habitual behaviors.<\/li>\r\n                                                                    <li>Altered activity was found in the sensorimotor putamen and the associative caudate in individuals with binge-eating disorder or bulimia nervosa, indicating changes in the structure of the grey matter and dopamine signaling, especially in the sensorimotor putamen.<\/li>\r\n                                                                    <li>Dopamine, a neurotransmitter released in response to reward, plays a significant role in habit formation, and the putamen in individuals with eating disorders had fewer dopamine receptors than healthy brains.<\/li>\r\n                                                                    <li>Future treatments targeting the implicated brain regions could potentially treat habitual behaviors underlying many psychiatric disorders, including eating disorders.<\/li>\r\n                                                <\/ul>\r\n            <\/div>\r\n            \n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Brain scans of people with binge-eating disorder or bulimia reveal altered activity in areas linked to habit formation, suggesting potential new treatments for these conditions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Researchers from Stanford University School of Medicine and the University of Pennsylvania found differences in brain structures related to dopamine signaling, which could help in understanding the brain mechanisms behind habit-driven eating behavior.<\/span><\/p>\n<h2><strong>Identifying Habit-Forming Brain Structures<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Researchers pinpointed two brain structures, the sensorimotor putamen and the associative caudate, as having a role in the formation of habits.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In order to locate these structures, they studied the links between the rat brain cortex and the striatum, utilizing high-resolution magnetic resonance imaging (MRI) data from a sample of 178 human subjects.<\/span><\/p>\n<h2><strong>Brain Activity Differences in Eating Disorders<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The researchers then studied the brains of 34 women with binge-eating disorder or bulimia nervosa and found altered activity in the sensorimotor putamen and the associative caudate.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Specifically, they found changes in the structure of the grey matter and in dopamine signaling, particularly in the sensorimotor putamen.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In individuals with eating disorders, the links between specific regions of the cortex and the habit-strengthening sensorimotor putamen were considerably more robust than in those without such disorders.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The degree of variation in brain scan results correlated directly with self-reported assessments of eating disorder severity.<\/span><\/p>\n<h2>                        <!-- <div class=\"container-c\"> -->\r\n                        <!-- <div class=\"row justify-content-between\"> -->\r\n                        <!-- <div class=\"col-post-800\"> -->\r\n                        <!-- start html -->\r\n                        <div class=\"blockquote-wapper\">\r\n                            <div>\r\n                                <span class=\"text_quot\">\r\n                                    <p>Researchers from Stanford University School of Medicine and the University of Pennsylvania found differences in brain structures related to dopamine signaling, which could help in understanding the brain mechanisms behind habit-driven eating behavior.<\/p>\n                                <\/span>\r\n\r\n                                <div class=\"quot_icon\">\r\n                                    <img decoding=\"async\" src=\"https:\/\/culture.org\/wp-content\/themes\/culture\/icons\/i_quot.svg\" type=\"image\/svg+xml\">\r\n                                <\/div>\r\n                            <\/div>\r\n\r\n                            <img decoding=\"async\" class=\"quot_tick\" src=\"https:\/\/culture.org\/wp-content\/themes\/culture\/icons\/i_quot_tri.svg\" type=\"image\/svg+xml\">\r\n                        <\/div>\r\n                        <!-- end html -->\r\n                        <!-- <\/div> -->\r\n                        <!-- <\/div> -->\r\n                        <!-- <\/div> -->\r\n                                    <\/h2>\n<h2><strong>Dopamine&#8217;s Role in Habit Formation<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Dopamine, a neurotransmitter released in response to reward, plays a significant role in habit formation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The researchers found that the putamen in individuals with eating disorders had fewer dopamine receptors than healthy brains.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">They suspect that increased dopamine release might reduce the sensitivity of these receptors and decrease their number.<\/span><\/p>\n<h2><strong>Potential New Treatments<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">These discoveries indicate that further investigation into novel therapies for binge-eating disorder and bulimia is warranted, given the historical resistance of these conditions to existing treatments.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Methods like deep-brain stimulation or transcranial magnetic stimulation might be employed to address the affected brain areas.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Moreover, the findings of this study suggest that upcoming interventions for a range of psychiatric disorders, not solely binge-eating disorder and bulimia, could focus on directly targeting brain circuitry.<\/span><\/p>\n<h2><strong>The Link Between Habit Learning and Binge Eating<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The study revealed that the degree of alteration in the sensorimotor putamen&#8217;s connectivity correlated with the severity of disordered eating behavior.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This suggests that the formation of a structural neural circuit links habit learning and binge eating behavior in humans.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The authors conclude that future treatments involving the modulation of these circuit-based mechanisms could potentially treat habitual behaviors underlying the treatment-resistant nature of many psychiatric disorders, not limited to eating disorders.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":18,"featured_media":155560,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[411],"tags":[],"class_list":["post-155559","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-special-interest"],"acf":[],"_links":{"self":[{"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/posts\/155559"}],"collection":[{"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/comments?post=155559"}],"version-history":[{"count":0,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/posts\/155559\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/media\/155560"}],"wp:attachment":[{"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/media?parent=155559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/categories?post=155559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/culture.org\/wp-json\/wp\/v2\/tags?post=155559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}